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Synthesis of a hydroxylated muricatacin analog related to squamocin

✍ Scribed by Shih-Hung Tsai; Pei-Chen Hsieh; Li-Lan Wei; Huey-Fen Chiu; Yang-Chang Wu; Ming-Jung Wu

Publisher: Elsevier Science
Year: 1999
Tongue: French
Weight: 126 KB
Volume: 40
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(99)00127-6

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✦ Synopsis

Comtxmnd 1 was synthesized in 9 steps and 5.5% overall yield lrom heptanal. The IC50 of comlxmnd 1 against tile growth of human hepatocarcinoma cell lines (Hep G2 and 2,2,15) are 22.0 and 21.8 p3vl, respectively.

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