Synthesis of a highly functionalized AB taxane ring system using 1,4-dioxene
✍ Scribed by Issam Hanna; Thierry Prangé; Rachida Zeghdoudi
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 223 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
A new approach to a highly functionalized 5,7,6-tricyclic core structure of guanacastepene has been developed using the tandem ring-closing metathesis reaction of dienynes as the key step.
Bicyclo[5.3.l]undecenone 2 corresponding to A and B rings in taxane diterpenes was synthesized. The eight-membered ring was constructed by a baseinduced intramolecular cyclization of twelve-membered lactam sulfoxides 15. 204 lja,b ya,bl,b2 isomer NC-S J K \*H,6 5 4 9 07 / 11' 1 3 10 -. 2 0 H R NHMe