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Synthesis of a functionalized chromane derivative via a TiCl4-mediated cyclization reaction

✍ Scribed by Leif R. Knöpke, Sebastian Reimann…


Book ID
120919752
Publisher
Springer Vienna
Year
2013
Tongue
English
Weight
789 KB
Volume
144
Category
Article
ISSN
0026-9247

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Stereoselective Synthesis of a Bicyclic Ketooxetane via a Thionium Ion-Mediated Cyclization Reaction. -Et-AlCl2-mediated cyclization of the Z-silyl enol ether onto the thionium ion trigger attached to the five-membered carbocyclic ring gives a good yield the desired bicyclic oxetane (II). It can be