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Efficient Synthesis of Highly Substituted Pyrrolin-4-ones via PIFA-Mediated Cyclization Reactions of Enaminones

✍ Scribed by Liang, Yongjiu; Pan, Wei; Yang, ; Dong, Dewen; Huang, Jie

Book ID
111921774
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
85 KB
Volume
9
Category
Article
ISSN
1523-7060

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✍ Kunyong Yang; Xiaohui He; Ha-soon Choi; Zhicheng Wang; David H. Woodmansee; Hong 📂 Article 📅 2008 🏛 Elsevier Science 🌐 French ⚖ 180 KB

An expedient one-pot synthesis of fused bicyclic 2,3-diaryl-pyrimidin-4(3H)-ones from three readily available components is described. The key step is a Lewis acid assisted cyclization reaction.