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Synthesis of a cytosine nucleoside of 2-amino-2-deoxy-β-D-xylofuranose

✍ Scribed by Melville L. Wolfrom; Shigeharu Inouye; Peter J. Conigliaro


Book ID
108308502
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
628 KB
Volume
42
Category
Article
ISSN
0008-6215

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6-Amino-3-(β-d-2-de­oxy-erythro-furanos­
✍ Sun, Zhenhua ;Lo, Wayne ;McLaughlin, Larry W. 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 302 KB

The title compound [systematic name: (2__R__,3__R__,5__R__)-5-(6-amino-2-fluoropyridin-3-yl)-2-(hydroxymethyl)-2,3,4,5-tetrahydrofuran-3-ol], C~10~H~13~FN~2~O~3~, is a C-nucleoside with fluorine replacing the O2 carbonyl of deoxycytidine (dC). The furanose ring adopts a C2′-__endo__ conformation, wh