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Synthesis of a cyanobacterial sulfolipid: confirmation of its structure, stereochemistry and anti-HIV-1 activity

โœ Scribed by Gordon, Dana M.; Danishefsky, Samuel J.


Book ID
121414720
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
742 KB
Volume
114
Category
Article
ISSN
0002-7863

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## An asymmetric synthesis leading to the enannomerically pwe dioxolane-T hm been achieved and its crystal structure has been demmined and compared to the previousty reported racemate. (-)-(I 'R,I'R)-L%xolane-T war found to have potent and selective anti-HIV activity in primary human lymphocytes.