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Synthesis of a coumarin based fluorescent amino acid

✍ Scribed by Guodong Sui; Péter Kele; Jhony Orbulescu; Qun Huo; Roger M. Leblanc

Book ID
110327814
Publisher
Springer Netherlands
Year
2001
Tongue
English
Weight
69 KB
Volume
8
Category
Article
ISSN
1573-3149

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A Mild Titanium-Catalyzed Synthesis of F
A Mild Titanium-Catalyzed Synthesis of Functionalized Amino Coumarins as Fluorescence Labels
✍ Lisa Wirtz; Uli Kazmaier 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 294 KB 👁 1 views

## Abstract In contrast to Brønsted and other Lewis acids ClTi(O__i__Pr)~3~ is especially suited to catalyze the formation of amino‐substituted coumarins from aminophenols and functionalized β‐oxo esters in a Pechmann condensation. This straightforward protocol allows the synthesis of fluorescence