Synthesis of a Chiral Tridentate Ligand from Proline and Its Application to Enantioselective Addition of Diethylzinc to Aldehydes.
β Scribed by Li-Hua Qiu; Zong-Xuan Shen; Jian-Feng Ge; Ya-Wen Zhang
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 18 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract A new class of chiral Ξ²βamino disulfides was synthesized from readily available and inexpensive starting materials by a straightforward method and their abilities as ligands were examined in the enantioselective addition of diethylzinc to aldehydes. Enantiomeric excesses of up to 99% ha