Synthesis of a carbon-14 labelled version of benzofuran GR151004B

✍ Scribed by Alan H. Wadsworth; Heather A. Mitchell; Ian Fellows; Derek R. Sutherland

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: French
• Weight: 376 KB
• Volume: 38
• Category: Article
• ISSN: 0022-2135
• DOI: 10.1002/(sici)1099-1344(199609)38:9<863::aid-jlcr895>3.0.co;2-0

✦ Synopsis

The 5HT1 receptor agonist GR151004B (a), labelled with carbon-I4 at C-3 of the benzofuran ring, was prepared in 19% overall yield in five steps from 5-bromo-2-methoxybenzoic [14C]acid (3b).