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Synthesis of a branched glycopeptide derivative containing terminal d-mannose 6-phosphate residues

✍ Scribed by Yoshitaka Ichikawa; Yuan Chuan Lee

Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 819 KB
Volume: 198
Category: Article
ISSN: 0008-6215
DOI: 10.1016/0008-6215(90)84295-6

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✦ Synopsis

A branched glycopeptide derivative incorporating two p-mannose 6-phosphate residues was prepared by coupling 6-aminohexyl 6-0-[bis(2,2,2-trichloroethoxy)phosphinyl]-a-o-mannopyranoside with N-acetyl-L-tyrosyl-L-aspart-oyldi-r_alanine followed by reductive deprotection of the phosphate group.

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