A new approach to the synthesis of β-glycosidically linked oligosaccharides containing 2-acetamido-2-deoxy-d-mannose residues
✍ Scribed by Emilio Micheli; Francesco Nicotra; Luigi Panza; Fiamma Ronchetti; L. Toma
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 169 KB
- Volume
- 139
- Category
- Article
- ISSN
- 0008-6215
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Hyaluronan (HA, l), a major component of the extracellular matrix of mam-\* Corresponding author.
Condensation of 3-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-beta-D- glucopyranosyl)-2,4,6-tri-O-acetyl-alpha-D-galactopyranosyl bromide (1) with benzyl 2-acetamido-3,6-di-O-benzyl-2-deoxy-alpha-D-glucopyranoside in boiling benzene and in the presence of mercuric cyanide afforded a trisaccharide that
2-Acetamido-3,4,6-tri-U-acetyl-2-deoxy-a-~-glucopyranosyl chloride was condensed with the iV-(benzyloxycarbonyl) derivatives of,