Synthesis of a bis-azido analogue of acromelic acid for radioisotope-free photoaffinity labeling and biochemical studies
β Scribed by Pi Sun; Guang Xing Wang; Kyoji Furuta; Masaaki Suzuki
- Book ID
- 108073945
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 116 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0960-894X
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A family of bis-[4Π-Azido-2,2Π:6Π,2Π-terpyridine platinum(II)] complexes with linear linkers of varying length have been synthesized. They have been designed to bis-intercalate into two DNA duplexes in close proximity, the azido groups allowing the sites of intercalation to be photoaffinity labeled.