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Synthesis and Biological Activity of Azido Analogues of 5,6-Dimethylxanthenone-4-acetic Acid for Use in Photoaffinity Labeling

✍ Scribed by Palmer, Brian D.; Henare, Kimiora; Woon, See-Tarn; Sutherland, Rachel; Reddy, Charu; Wang, Liang-Chuan S.; Kieda, Claudine; Ching, Lai-Ming


Book ID
111909815
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
338 KB
Volume
50
Category
Article
ISSN
0022-2623

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Synthesis, azido-tetrazole equilibrium s
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1-(2-Azido-6-chloropyrid-4-yl)-3-phenylurea was synthesized using known methods. Azido-tetrazole equilibrium for this compound was studied in various solvents, and the azide tautomer was found to be largely predominant. However, in water solution, it is suspected to exist in the tetrazole form in a