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Synthesis of 9-Substituted Tetrahydrodiazepinopurines: Studies toward the Total Synthesis of Asmarines

โœ Scribed by Pappo, Doron; Shimony, Shiri; Kashman, Yoel


Book ID
120441814
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
288 KB
Volume
70
Category
Article
ISSN
0022-3263

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A synthetic approach towards the synthes
โœ Doron Pappo; Amira Rudi; Yoel Kashman ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 74 KB

Asmarines are marine alkaloids with the unique N(10)-hydroxytetrahydro [1,4] diazepino[1,2,3-g,h]purine system and interesting biological activity. The heterotricyclic system was prepared from substituted purines. CH-correlations were found to be an easy way to determine the mode of cyclisation in t