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Synthesis of 9-[1-Benzyl-5-(alkylsulfonyl)-1H-2-imidazolyl] perhydro-1,8-acridinediones.

✍ Scribed by F. Hadizadeh; N. Mehri


Publisher
John Wiley and Sons
Year
2006
Weight
13 KB
Volume
37
Category
Article
ISSN
0931-7597

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Abstract

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Synthesis of 9-[1-benzyl-5-(alkylsulfony
✍ F. Hadizadeh; N. Mehri 📂 Article 📅 2006 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 57 KB

## Abstract magnified image Tricyclic dihydropyridines like ZM244085 are potential K~ATP~ channel openers. In this study 3‐cyanophenyl ring of ZM244085 was replaced with imidazolyl ring. So, 9‐[1‐benzyl‐5‐(alkylsulfonyl)‐1__H__‐2‐imidazolyl]perhydro‐1,8‐acridinediones (**5d‐f**) were synthesized f

Synthesis of novel 2-(2-methylsulfonyl-1
✍ Azita Javidnia; Tahmineh Akbarzadeh; Loghman Firoozpour; Mehdi Khoobi; Abbas Sha 📂 Article 📅 2010 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 86 KB 👁 1 views

## Abstract Starting from 5‐hydroxymethyl‐2‐mercapto‐1‐methyl‐1__H__‐imidazole (1), a series of 2‐(1‐methyl‐2‐methylsulfonyl‐1__H__‐imidazol‐5‐yl)‐5‐alkylthio and 5‐alkylsulfonyl‐1,3,4‐thiadiazole derivatives (**9a**, **9b**, **9c**, **9d** and **10a**, **10b**, **10c**, **10d**) were prepared as p