✦ LIBER ✦

Synthesis of novel 2-(2-methylsulfonyl-1-methyl-1H-imidazol-5-yl)-5-(alkylsulfonyl)-1,3,4-thiadiazoles

✍ Scribed by Azita Javidnia; Tahmineh Akbarzadeh; Loghman Firoozpour; Mehdi Khoobi; Abbas Shafiee; Alireza Foroumadi

Publisher: Journal of Heterocyclic Chemistry
Year: 2010
Tongue: English
Weight: 86 KB
Volume: 48
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.535

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✦ Synopsis

Abstract

Starting from 5‐hydroxymethyl‐2‐mercapto‐1‐methyl‐1__H__‐imidazole (1), a series of 2‐(1‐methyl‐2‐methylsulfonyl‐1__H__‐imidazol‐5‐yl)‐5‐alkylthio and 5‐alkylsulfonyl‐1,3,4‐thiadiazole derivatives (9a, 9b, 9c, 9d and 10a, 10b, 10c, 10d) were prepared as potential antimicrobial agents. The structure of the obtained compounds was confirmed by NMR, IR, Mass spectroscopy, and elemental analysis. J. Heterocyclic Chem., (2010)

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