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Synthesis of 6h-pyrido[4,3-b]carbazoles

✍ Scribed by Sandeep P. Modi; Todd McComb; Abdel-Hadi Zayed; R. Christopher Oglesby; Sydney Archer


Book ID
108371829
Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
514 KB
Volume
46
Category
Article
ISSN
0040-4020

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A synthesis of 5-hydroxymethyl-ll-methyl-6H-pyrido[4,3-b]carbazole and the correspondinq 5-formvl derivative. 17-oxoellioticine.3 is described, the key feature of which-is the use of the KrohnkeI aldehyde synthesis to effect the debenzylation of a p-nitrobenzyl-pyridinium salt under mild conditions.