Synthesis of 6-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones via directed lithiation of 2-substituted 5-aminopyridine derivatives
β Scribed by Rewcastle, Gordon W.; Denny, William A.; Winters, R. Thomas; Colbry, Norman L.; Showalter, H. D. Hollis
- Book ID
- 120830278
- Publisher
- Royal Society of Chemistry
- Year
- 1996
- Weight
- 872 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1472-7781
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract magnified image The thienopyridine derivative **2**, obtained from reaction of acetoacetic ester with **1** in the presence of tin tetrachloride, was treated with triphenylphosphine in hexachloroethane and Et~3~N to give iminophosphorane **3**. Iminophosphorane **3** reacted with pheny
## Abstract A series of new 2βsubstituted 3β(4βchlorophenyl)β5,8,9βtrimethylthieno[3β²,2β²:β5,6]pyrido[4,3β__d__]pyrimidinβ4(3__H__)βones **8** were synthesized __via__ an azaβ__Wittig__ reaction. Phosphoranylideneamino derivatives **6a** or **6b** reacted with 4βchlorophenyl isocyanate to give carbo