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Synthesis of 6-substituted 5-cyano-7-hydroxy-2-carboxybenzofurans

✍ Scribed by Simon J. Teague; Simon Barber

Publisher: Elsevier Science
Year: 2010
Tongue: French
Weight: 525 KB
Volume: 51
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2010.07.020

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✦ Synopsis

Methods for the synthesis of 5-cyano-7-hydroxy-2-carboxybenzofurans bearing a variety of substituents at the 6-position are outlined. The scope and limitations of lithiation processes, electrophilic substitutions, and pericyclic reactions are investigated.

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