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Synthesis of 6-amino-2-(p-aminophenyl)-4-phenylquinazoline

✍ Scribed by V. F. Sedova; O. P. Shkurko


Publisher
Springer US
Year
1995
Tongue
English
Weight
316 KB
Volume
31
Category
Article
ISSN
0009-3122

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Synthesis of 4-(2-diphenylphosphino-1-na
✍ V Gautheron Chapoulaud; J Audoux; N PlΓ©; A Turck; G QuΓ©guiner πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 168 KB

We describe a multistep synthesis leading in a good yield to the title compound. The biaryl linkage was formed in a Pd-catalysed coupling of 2-phenyl-4-chloroquinazoline with 2-methoxy-l-naphthylboronic acid. A further metal-catalysed reaction gave the formation of the naphthylphosphorus bond allowi