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Synthesis of 6-[18F]fluoro-PBR28, a novel radiotracer for imaging the TSPO 18 kDa with PET

✍ Scribed by Annelaure Damont; Raphaël Boisgard; Bertrand Kuhnast; Frédéric Lemée; Guillaume Raggiri; Alana M. Scarf; Eleonora Da Pozzo; Silvia Selleri; Claudia Martini; Bertrand Tavitian; Michael Kassiou; Frédéric Dollé


Book ID
113495875
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
461 KB
Volume
21
Category
Article
ISSN
0960-894X

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Radiosynthesis of [18F]PBR111, a selecti
✍ Frédéric Dollé; Françoise Hinnen; Annelaure Damont; Bertrand Kuhnast; Christophe 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 137 KB

## Abstract PBR111 (2‐(6‐chloro‐2‐(4‐(3‐fluoropropoxy)phenyl)imidazo[1,2‐__a__]pyridin‐3‐yl)‐__N__,__N__‐diethylacetamide) is a novel, reported, high‐affinity and selective ligand for the translocator protein (18 kDa). PBR111 has been labelled with fluorine‐18 (half‐life: 109.8 min) using our Zymat