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Synthesis of 5H-pyrazolo[5,1-c][1,4]benzodiazepine

โœ Scribed by Lucia Cecchi; Guido Filacchioni


Book ID
112127148
Publisher
Journal of Heterocyclic Chemistry
Year
1983
Tongue
English
Weight
217 KB
Volume
20
Category
Article
ISSN
0022-152X

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Synthesis of 1,5-diaryl-3-methyl-1 H-pyr
โœ Lucia Cecchi; Vittoria Colotta; Fabrizio Melani; Giovanna Palazzino; Guido Filac ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 563 KB

Some 1,5-diaryl-3-methyl-1H-pyrazolo[4,5-c]isoquinolines were synthesized and tested for their ability to displace [3H]clonazepam or [3H]Ro 5-4864 from their specific binding on the central and peripheral benzodiazepine receptors. None of the tested compounds showed any activity as central binding i