Synthesis of 5′,11-dihydroxy-Δ8-tetrahydrocannabinol
✍ Scribed by John W. Huffman; Ming-Jung Wu; W.Kenneth Banner; Dong Dai
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 706 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
1/3,6gEpoxy-hexahydrocannabinol acetate (1) in the presence of borontrifluoride rearranged to 6-oxo-hexahydrocannabinol acetate (3b) and to the aldehyde (4). Hydroboratlon of AE-THC gave the 6-hydroxy hexahydrocannabinols 5a and &I. The latter was converted into A+THC (11). This THC isomer shows no
Condensatzon of I,&bzs(trunethylszloxyl-I-methoxybutadiene wzth the aced chloride ;z gave methyl olivetolate (;?I. Condensatzon of 22 wzth (+I-p-mentha-2,8-dzenl-01 gave methyl Al-tetrahydrocannabinolate (14) zn 55% zsolated yzeld. Alkalzne hydrolyses of lg gave Al-tetrahydrocannabznol-72, Al-THCI.