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A biomimetic synthesis of Δ1-tetrahydrocannabinol

✍ Scribed by T.H. Chan; T. Chaly

Publisher: Elsevier Science
Year: 1982
Tongue: French
Weight: 206 KB
Volume: 23
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)87498-5

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✦ Synopsis

Condensatzon of I,&bzs(trunethylszloxyl-I-methoxybutadiene wzth the aced chloride ;z gave methyl olivetolate (;?I. Condensatzon of 22 wzth (+I-p-mentha-2,8-dzenl-01 gave methyl Al-tetrahydrocannabinolate (14) zn 55% zsolated yzeld. Alkalzne hydrolyses of lg gave Al-tetrahydrocannabznol-72, Al-THCI. The synthesis zs patterned after the bzogenesis of 2.

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