𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hashish : Synthesis of (−)-7-hydroxy-Δ1(6)-tetrahydrocannabinol

✍ Scribed by Klaus K. Weinhardt; Raj K. Razdan; Haldean C. Dalzell

Publisher
Elsevier Science
Year
1971
Tongue
French
Weight
142 KB
Volume
12
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

It is well documented 2,3,4,5 that the primary reaction in the metabolism of A'-and Al(e) -THCs* (la and 2a) is oxidation to the 7-hydroxy derivatives J& and &.

📜 SIMILAR VOLUMES

A urinary metabolite of Δ1-tetrahydrocan
A urinary metabolite of Δ1-tetrahydrocannabinol. The first synthesis of 4′′-hydroxy-Δ1-tetrahydrocannabinol-7-oic acid labelled with deuterium
✍ Maria Szirmai; Helena Odqvist; Magnus M. Halldin 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 773 KB

The first synthesis of 4"-hydroxy-A1-THC-7-oic acid, one of the three major metabolites of AI-THC identified in human urine is discussed. Methyl 4-(3,5-dihydroxyphenyl)butanoate (8) was prepared from 3,5-dihydmxybenzoic acid in an overall yield of 15%. 8 was condensed with a terpene synthon (9) unde