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Synthesis of 5-fluoro-2-methyl-3-(2-trifluoromethyl-1,3,4-thiadiazol-5-yl)-4(3H)-quinazolinone and related compounds with potential antiviral and anticancer activity

✍ Scribed by Cyril Párkányi; Hui Liang Yuan; Bo H. E. Strömberg; Ariella Evenzahav


Book ID
112130342
Publisher
Journal of Heterocyclic Chemistry
Year
1992
Tongue
English
Weight
288 KB
Volume
29
Category
Article
ISSN
0022-152X

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Synthesis of 5-chloro-2-methyl-3-(5-meth
✍ Cyril Párkányi; Duran S. Schmidt 📂 Article 📅 2000 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 313 KB

## Abstract Eight new 2‐methyl‐4(3__H__)‐quinazolinones **(8a‐8d, 9c, 9d, 10c, 10d)** with one or two chlorine atoms in the benzene ring and a 5‐methyl‐1,3‐thiazol‐2‐yl, 4‐methyl‐1,3‐thiazol‐2‐yl, and 5‐ethyl‐1,3,4‐thiadiazol‐2‐yl substituent in position 3 of the heterocyclic ring were synthesized