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Synthesis of 5-benzyl-4-aryl-octahydro-1H-benzo[b][1,5]diazepin-2-ones as potent antidepressant and antimicrobial agents

✍ Scribed by Babu, Mariappan; Pitchumani, Kasi; Ramesh, Penugonda

Book ID
121555347
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
423 KB
Volume
23
Category
Article
ISSN
1054-2523

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## Abstract The reaction of 1‐aryl‐3‐(dimethylamino)‐1‐propanones 1 with one equivalent of 4,5‐diamino‐1__H__‐pyrimidin‐6‐ones 2, in acidic medium, leads to the formation of 4‐aryl‐2,3,6,7‐tetrahydro‐1__H__‐pyrimido[4,5‐__b__]‐[1,4]diazepin‐6‐ones 3. The structure elucidation of the products is bas