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Synthesis of 4,5,6-trisubstituted 2,3-pyridinediones via Mannich reaction and oxidation–Michael addition of 3-hydroxy-2(1H)-pyridinones

✍ Scribed by Wen Lin Xie, Chuang Ping Xiao, Ling Xie, Ying Zhou, Xue Feng Li, Xu Fu Tang, Chun Tao Yuan, Ming Hua Qiu


Book ID
118809652
Publisher
Springer Netherlands
Year
2012
Tongue
English
Weight
227 KB
Volume
38
Category
Article
ISSN
0922-6168

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ChemInform Abstract: Synthesis of 6-Subs
✍ Miao-Sheng Li; Lian-Quan Gu; Zhi-Shu Huang; Shao-Hua Xiao; Lin Ma 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

Synthesis of 6-Substituted-3-hydroxy-4(1H)-pyridinones: Oxidation-Michael Addition of 3-Hydroxy-4(1H)-pyridinones. -The oxidation of pyridinones of type (I) with Ag 2 O involving alcohols (II) is reported for the first time. The resulting pyridinediones subsequently undergo Michael addition with thi