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Synthesis of 4-Substituted Indoles from o-Nitrotoluenes

โœ Scribed by I. Kruse, Lawrence


Book ID
118258512
Publisher
Japan Institute of Heterocyclic Chemistry
Year
1981
Tongue
English
Weight
163 KB
Volume
16
Category
Article
ISSN
0385-5414

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๐Ÿ“œ SIMILAR VOLUMES


Useful synthesis of 4-substituted indole
โœ Ponticello, Gerald S.; Baldwin, John J. ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› American Chemical Society ๐ŸŒ English โš– 484 KB
6-substituted indoles from o-halonitrobe
โœ Allan N. Tischler; Thomas J. Lanza ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 186 KB

Summarv: o-Chloro-and o-bromonitrobenzenes are efficiently converted to 6-substituted indoles in a four step synthesis, proceeding through o-trimethylsilylethynylnitrobenzenes, o-nitrophenylacetaldehydc dimethylacetals and o-aminophenylacetaldehyde dimethylacetals as intermediates.

Synthesis of 2-substituted indoles
โœ S. I. Zav'yalov; A. G. Zavozin; O. V. Dorofeeva; E. E. Rumyantseva ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 240 KB