Hydrazonoyl bromides 1a-c react with 5-amino-3phenyl-1H-pyrazole, 5-amino-1H-1,2,4-triazole, 2aminopyridine, 2-aminopyrimidine, and 2-aminobenzimidazole to afford the corresponding imidazo[1,2-b]pyrazoles 10, imidazo[1,2-b]-1,2,4-triazoles 11, imidazo[1,2-a]pyridines 16, imidazo[1,2-a]pyrimidines 17
Synthesis of 4-substituted imidazo[1,2-a]quinoxalines
β Scribed by Clemens Lamberth
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 24 KB
- Volume
- 341
- Category
- Article
- ISSN
- 1615-4150
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π SIMILAR VOLUMES
and 3-aminopyrazole and 3-amino-1,2,4-triazole provide convenient access to biologically relevant 3H-imidazo[1,2-b]pyrazoles and a 5H-imidazo[2,1-c][1,2,4]triazole.
## Abstract Some 1,2,4βtriazolo[4,3β__a__]quinoxalines 1β10, and 1,2,4βtriazino[4,3β__a__]quinoxalines 11β12 were prepared and biologically evaluated for their binding at the benzodiazepine receptor (BZR) in rat cortical membranes. The BZR affinity of 1β10 demonstrates that the presence of a proton
Benzofuroylhydroxamoyl chloride (3) reacted with acrylonitrile, N-tolylmaleimide and active methylene compounds to afford the isoxazoline 4, the pyrrolidino13,4-d]isozazoline 5 and the isoxazole derivatives 6, 7, respectively. Nitrosoirnidazo[ 1,2-alpyridines 10 and the imidazo[ 1,2-alpyrimidine 12