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Synthesis of 4-substituted-1,2,3,4-tetrahydro-β-carbolines via intramolecular radical cyclisation and Heck reaction

✍ Scribed by Arasambattu K Mohanakrishnan; Panayencheri C Srinivasan


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
182 KB
Volume
37
Category
Article
ISSN
0040-4039

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Stereospecific synthesis of trans-1,3-di
✍ Frank Ungemach; Mike DiPierro; Robert Weber; James M. Cook 📂 Article 📅 1979 🏛 Elsevier Science 🌐 French ⚖ 241 KB

The stereospecific synthesis of trans-1,3-disubstituted-1,2,3,4\_tetrahydro $-carbolines has been accomplished in good yield by a two step sequence which involves Pi&et-Spengler condensation of Nb-benzyltryptophan methyl: ester with aldehydes, followed by removal of the 2-benzyl moiety from the corr