Synthesis of 4-Methyldienoates Using a Vinylogous Horner−Wadsworth−Emmons Reagent. Application to the Synthesis of Trichostatic Acid
✍ Scribed by Markiewicz, John T.; Schauer, Douglas J.; Löfstedt, Joakim; Corden, Steven J.; Wiest, Olaf; Helquist, Paul
- Book ID
- 126853447
- Publisher
- American Chemical Society
- Year
- 2010
- Tongue
- English
- Weight
- 861 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
An improved synthesis of the C(I)-C( ) (E,Z)-dienoate segment of (+)-damavaricin D precursor 3 was accomplished using the unsaturated phosphonate reagent 9 in a (Z)-selective vinylogous Horner-Wadsworth-Emmons reaction.
An Improved Synthesis of the (E,Z)-Dienoate Precursor of (+)-Damavaricin D via a Vinylogous Horner-Wadsworth-Emmons Reaction. -An improved synthesis of the title compound, the DmD intermediate (IV), is achieved by a (Z)-selective olefination of the aldehyde (III) using the vinylogous Horner-Wadswor