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Synthesis of 4-hydroxy-2(1H)-pyridones from azomethines and substituted dialkylmalonates

✍ Scribed by S. Kafka; T. Kappe

Book ID
104950057
Publisher
Springer Vienna
Year
1997
Tongue
English
Weight
755 KB
Volume
128
Category
Article
ISSN
0026-9247

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## Abstract The reaction of 4 with substituted diethyl malonates 5a, or β€œmagic malonates” (bis‐2,4,6‐trichlorophenylmalonates 5b) leads to 4‐hydroxy‐2(1__H__)‐pyridones 6. The azomethines 4 are prepared __via__ the __Strecker__ compounds 3 starting with methyl ketones 1, anilines, and potassium cya