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Synthesis of 4-carboethoxy-4-oxazolin-2-ones from 3-nosyloxy-2-ketoesters

โœ Scribed by Robert V. Hoffman; M.Catherine Johnson; John F. Okonya

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
297 KB
Volume
39
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

3-Nosyloxy-2-ketoesters, available from 2-ketoesters, react efficiently with methyl carbamate and tosic acid in refluxing toluene to provide 4-carboalkoxy-4oxazolin-2-ones in good yields (41-84%).

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