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Synthesis of 4-Aryl-1,7-naphthyridine-2(1H)-thiones by the Electrocyclic Reaction of 4-(1-Arylalk-1-enyl)-3-isothiocyanatopyridines Generated in situ from the Corresponding Isocyanides

✍ Scribed by Kazuhiro Kobayashi; Taketoshi Kozuki; Teruhiko Suzuki


Book ID
112098266
Publisher
John Wiley and Sons
Year
2012
Tongue
German
Weight
164 KB
Volume
95
Category
Article
ISSN
0018-019X

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Synthesis of 2,4,8-Trisubstituted 1,7-Na
✍ Kazuhiro Kobayashi; Taketoshi Kozuki; Shuhei Fukamachi; Hisatoshi Konishi 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 German ⚖ 153 KB

## Abstract A convenient method for the synthesis of 2,4,8‐trisubstituted 1,7‐naphthyridines **6** by the reaction of (__E__)‐4‐(1‐aryl‐2‐methoxyethenyl)‐3‐isocyanopyridines **4**, which could be easily prepared from commercially available 3‐aminopyridine __via__ aroylation of lithium (4‐lithiopyri