Synthesis of 4-[3-(1H)-indolyl]-2-[N-guanidinomethyl]thiazole dihydrochloride
β Scribed by Michael P. Zawistoski
- Book ID
- 112129553
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1990
- Tongue
- English
- Weight
- 192 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
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## Abstract magnified image Some new derivatives of spiro[3__H__βindoleβ3,2β²βthiazolidine]β2,4β²(1__H__)βdione with the heterocyclic ring such as substituted thiazole and 1,2,4βoxadiazole attached to the indolinone ring __via__ CH~2~ linkage has been synthesized in moderate yields. The synthesis ha
## Abstract The synthesis of 5βFluoroβ3β[3β[4β(2β[^14^C]β5βmethoxyβ4βpyrimiβdinyl)β1βpiperazinyl]propyl]β1Hβindole dihydrochloride (5) was achieved by coupling [^14^C] formamidine acetate (1) and dimethylmethoxymalonate in methanol containing sodium methoxide at 60Β°C to provide 2β[^14^C] 4,6βdihydr