Synthesis of 3,5‐Diphenyl‐1H‐Pyrazoles
✍ Scribed by Bhat, B. A.; Puri, S. C.; Qurishi, M. A.; Dhar, K. L.; Qazi, G. N.
- Book ID
- 115450108
- Publisher
- Taylor and Francis Group
- Year
- 2005
- Tongue
- English
- Weight
- 102 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0039-7911
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## Abstract magnified image Compound of 4‐(ethoxycarbonyl)‐1,5‐diphenyl‐1__H__‐pyrazole‐3‐carboxylic acid **2** was obtained from the reaction of ethyl 4,5‐dioxo‐2‐phenyl‐4,5‐dihydrofuran‐3‐carboxylate and 1‐benzylidene‐2‐phenylhydrazine. A number of substitute pyrazole dicarboxylic acid derivative
## Abstract magnified image 1,5‐Diphenyl‐1__H__‐pyrazole‐3,4‐dicarboxylic acid‐4‐ethyl ester **2**, obtained from the 4‐ethoxycarbonyl‐5‐phenyl‐2,3‐furandione **1** and __N__‐benzylidene‐__N__′‐phenyl hydrazine, was converted __via__ reactions of its acid chloride **3** with various alcohols or N‐
## Abstract magnified image A “one‐pot” method for the synthesis of __N__‐(1,3‐diphenyl‐1__H__‐pyrazol‐5‐yl)amides was developed by cyclization of benzoylacetonitrile (**1**) and phenylhydrazine in neat condition followed by acylation. The corresponding __N__‐(1,3‐diphenyl‐1__H__‐pyrazol‐5‐yl)amide