Three selectively labeled propynes were prepared either with deuterium or carbon-13 at position 3 and doubly labeled with carbon-13 at positions 1 and 2 by an alkylation reaction from the corresponding labeled or unlabeled monolithio acetylides and dimethylsulfates. Their lithiation with nBuLi gave
β¦ LIBER β¦
Synthesis of [3',5'-13C2]tyrosine and its use in the synthesis of specifically labeled tyrosine analogs of oxytocin and arginine vasopressin and their 2-D-tyrosine diastereoisomers
β Scribed by Viswanatha, Venkatappa; Hruby, Victor J.
- Book ID
- 126223243
- Publisher
- American Chemical Society
- Year
- 1979
- Tongue
- English
- Weight
- 764 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0022-3263
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## Abstract Sumitriptan (1), a nonβselective 5βHT~1B/1D~ agonist is an effective therapeutic agent for the acute treatment of migraine, but it is contraindicated for use in patients with known heart disease. The first Selective Serotonin One F Receptor Agonist (SSOFRA), 5β(4β²βfluorobenzβamido)β3β(_