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Synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones using ZrOCl2/mont K10 under microwave assisted solvent-free conditions

✍ Scribed by Vijayakumar, B.; Ranga Rao, G.


Book ID
113072203
Publisher
Springer
Year
2011
Tongue
English
Weight
564 KB
Volume
19
Category
Article
ISSN
1380-2224

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Synthesis of 3,4-dihydropyrimidin-2(1H)-
✍ Atul Kumar; Ram Awatar Maurya πŸ“‚ Article πŸ“… 2007 πŸ› Elsevier Science 🌐 English βš– 164 KB

A Ziegler-Natta catalyst system (TiCl 4 -MgCl 2 /magnesium chloride-methanol adduct) was efficiently found to catalyze the three component Biginelli reaction of an aldehyde, ␀-keto ester, and urea or thiourea under solvent free conditions to afford the corresponding 3,4-dihydropyrimidin-2-(1H)-ones