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Synthesis of 3-(trans-2'-Nitrocyclopropyl)alanine, a Constituent of the Natural Peptide-Lactone Hormaomycin

โœ Scribed by Zindel, Juergen; de Meijere, Armin


Book ID
121325524
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
782 KB
Volume
60
Category
Article
ISSN
0022-3263

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โœ Langschwager, Wolf ;Hoffmann, H. Martin R. ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 605 KB

tautomer I 4-Oxocarboxylic acids I Keto-cyclol tautomerism (2-Oxocyclohexyl)acetic acid 10 was converted into bicyclic alkoxy y-lactones 12a-d via intermediate chloro lactone 11 and alkanolysis. Similarly, lactones 15a, b and 18 were prepared. In contrast, simple ring-chain tautomerism directly affo