Synthesis of 3-silyl-2(5H)-furanone by rhodium-catalyzed cyclocarbonylation

✍ Scribed by Yukimasa Fukuta; Isamu Matsuda; Kenji Itoh

• Book ID: 104211728
• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 87 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)02234-6

✦ Synopsis

3-Silyl-2(5H)-furanones are readily formed by the rhodium-catalyzed cyclocarbonylation of propargyl alcohol derivatives bearing a trialkylsilyl group on the terminal sp-carbon under hydroformylation conditions. The following two requirements must be satisfied for the success of this protocol; (i) the presence of a silyl group on the sp-carbon, and (ii) the presence of a catalytic amount of Rh 4 (CO) 12 .