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Synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamide-derived antagonists of CC chemokine receptor 2 (CCR2)

✍ Scribed by Michael G. Yang; Zili Xiao; Qing Shi; Robert J. Cherney; Andrew J. Tebben; George V. De Lucca; Joseph B. Santella III; Ruowei Mo; Mary Ellen Cvijic; Qihong Zhao; Joel C. Barrish; Percy H. Carter


Book ID
113496500
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
420 KB
Volume
22
Category
Article
ISSN
0960-894X

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## Abstract The 1‐cyclohexyl substituted 3‐aminopyrrolidine derivatives having a morpholine or thiomorpholine at the C‐4 position of the cyclohexyl group (II) are found to be good CCR2 antagonists.