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Synthesis of 3-O-[(3R)-3-acyloxytetradecanoyl]-2-deoxy-2-[(3R)-3-hydroxy- tetradecanamido]-4-O-phosphono-d-glucose derivatives related to bacterial lipid A

โœ Scribed by Yuji Ogawa; Yushun Fujishima; Hideharu Ishida; Makoto Kiso; Akira Hasegawa


Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
571 KB
Volume
197
Category
Article
ISSN
0008-6215

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โœฆ Synopsis


Compound 14 had m.p. 123-124", [r& f7.9" (c 0.6, dichloromethane).


๐Ÿ“œ SIMILAR VOLUMES


A convenient synthesis of 2-deoxy-2-[(R)
โœ Ingolf Macher ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 417 KB

The crystalline tris(hydroxymethyl)ainomethane ("Tris") salt of 2-deoxy-2-[(R)-3-hydroxytetradecanamido]-3-0-[(R)-3-hydroxytetradecanoyl]-cY-D-glucopyranose 1 -phosphate (lipid X) has been synthesised from 2-animo-2-deoxy-D-glucose hydrochloride in five steps in -50% overall yield. The key step was