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Synthesis of 3-Hydroxyethyl-4-oxoazetidin-2-ylphosphonate Derivatives: Potential Precursors to Carbapenem and a-Aminophosphonic Acid Derivatives

✍ Scribed by Shiozaki, Masao; Masuko, Hidekazu


Book ID
115465655
Publisher
Japan Institute of Heterocyclic Chemistry
Year
1984
Tongue
English
Weight
53 KB
Volume
22
Category
Article
ISSN
0385-5414

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3R,4R-and 3S,4S)-3-Methyl-4-(3%-O-methylgalloyloxy)octanoic acid (2b), the corresponding methyl ester (2c) and the straight galloyl derivative, (3R,4R-and 3S,4S)-3-methyl-4-galloyloxyoctanoic acid (2a) were synthesised from cis-oak lactone (1). Analysis by TLC and mass spectrometry established that