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Synthesis of 3-disubstituted 3H-4,1,2-benzothiadiazines and 3-disubstituted 3H-4,1,2-benzothiadiazine 4,4-dioxides

✍ Scribed by A. Balbi; M. Mazzei; E. Sottofattori


Book ID
112130146
Publisher
Journal of Heterocyclic Chemistry
Year
1991
Tongue
English
Weight
235 KB
Volume
28
Category
Article
ISSN
0022-152X

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📜 SIMILAR VOLUMES


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A simple method for the preparation of 4,4-disubstituted-3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2dioxides is described. Treatment of N-sulfonyl ketimines 2 and 3 with different carbon nucleophiles afforded the corresponding of 4,4-disubstituted-3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides 1 i

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## Abstract A new method for the preparation of 4‐substituted 3,4‐dihydro‐1__H__‐2,1,3‐benzothiadiazine 2,2‐dioxides is described. Treatment of __t__‐butyl __N__‐phenylsulfamoylcarbamate derivatives (**1**) with different aldehydes afforded the corresponding intramolecular cyclized products **2** u