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Synthesis of 3-bromo- and 3-chloro-1-methyl-4-phenyl-4-propionoxypiperidines as potential analgetics

โœ Scribed by Carabateas, Philip M.


Book ID
126895284
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
135 KB
Volume
13
Category
Article
ISSN
0022-2623

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Synthesis of 3-methyl-4-phenyl-3-butenam
โœ U. Valcavi ๐Ÿ“‚ Article ๐Ÿ“… 1974 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 230 KB ๐Ÿ‘ 1 views

## Abstract The syntheses of 3โ€methylโ€4โ€phenylโ€3โ€butenamide, an hypolipemic compound, labelled 1โ€^14^C (VIII) and N,Nโ€dideutero (XI) are described. The 2โ€methylโ€3โ€phenylโ€2โ€propenyl chloride (VI), reacting with cuprous cyanideโ€^14^C, gave the 3โ€methylโ€4โ€phenylโ€3โ€butenonitrileโ€1โ€^14^C (VII) which, tr