Synthesis of 3-aryl-2-[hydroxy(diaryl)methyl]-4-oxo-3,4-dihydroquinazolines
✍ Scribed by L. A. Shemchuk; V. P. Chernykh; D. V. Levashov; K. M. Sytnik; L. M. Shemchuk
- Book ID
- 111465551
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2010
- Tongue
- English
- Weight
- 182 KB
- Volume
- 46
- Category
- Article
- ISSN
- 1070-4280
No coin nor oath required. For personal study only.
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In the title compound, C 15 H 17 N 3 OS 2 , the piperidine ring adopts a chair conformation. Weak intermolecular C-HÁ Á ÁO hydrogen bonds link the molecules into chains along the c axis and further stability is provided by offsetstacking interactions [centroid separations = 3.73 (2)-3.78 (2) A ˚] in
## Abstract The cyclization of phenacyl anthranilate has been studied with the aim to develop the synthesis of 2‐(2′‐aminophenyl)‐4‐phenyloxazole. However, a different course of the reaction than expected was observed. 2‐Phenyl‐2‐hydroxymethyl‐4‐oxo‐1,2,3,4‐tetrahydroquinazoline (**3a**) was formed