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Synthesis of 3-aminoindole derivatives: combination of Thorpe–Ziegler cyclization and unexpected allylindium-mediated decyanation

✍ Scribed by Yu Mi Kim; Ko Hoon Kim; Sunhong Park; Jae Nyoung Kim


Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
776 KB
Volume
52
Category
Article
ISSN
0040-4039

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✦ Synopsis


a-Anilinonitriles were unexpectedly converted to 3-iminodihydroindoles via the Thorpe-Ziegler cyclization during the benzoylation. 3-Iminodihydroindoles were transformed to 3-aminoindoles in good yields via an allylindium-mediated decyanative aromatization.


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