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Synthesis of 3-Amino-1,2,4-benzothiadi- azine 1,1-Dioxides via a Tandem Aza-Wittig/Heterocumulene Annulation

โœ Scribed by Blackburn, Christopher; Achab, Abe; Elder, Amy; Ghosh, Shomir; Guo, Jianping; Harriman, Geraldine; Jones, Matthew


Book ID
120934377
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
257 KB
Volume
70
Category
Article
ISSN
0022-3263

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## Abstract magnified image The carbodiimides **2**, obtained from reactions of iminophosphorane **1** with isocyanates, reacted with hydrazine to give selectively 3โ€aminoโ€2โ€arylaminobenzothieno[3,2โ€__d__]pyrimidinโ€4(3__H__)โ€ones **4**. Reactions of **4** with triphenylphosphine, hexachloroethane,

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## Abstract magnified image Carbodiimide **2**, obtained from azaโ€Wittig reaction of iminophosphorane **1** with aromaic isocyanate, reacted with ฮฑโ€amino ester in the presence of catalytic amount of sodium ethoxide to give selectively new tetracyclic benzothieno[3,2โ€d]โ€imidazo[1,2โ€a]pyrimidineโ€2,5