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Parallel Solid-Phase Synthesis of 2-Imino-4-oxo-1,3,5-triazino[1,2- a ]benzimidazoles via Tandem Aza-Wittig/Heterocumulene-Mediated Annulation Reaction

✍ Scribed by Hoesl, Cornelia E.; Nefzi, Adel; Houghten, Richard A.


Book ID
125535255
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
111 KB
Volume
5
Category
Article
ISSN
1520-4766

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An abnormal aza-Wittig reaction was observed when resin-bound iminophosporanes were treated with aryl isocyanates on the solid-phase. The mechanism of the reaction may involve the loss of triphenylphosphinimide instead of triphenylphosphinoxide, resulting in the formation of isocyanates instead of c