Parallel Solid-Phase Synthesis of 2-Imino-4-oxo-1,3,5-triazino[1,2- a ]benzimidazoles via Tandem Aza-Wittig/Heterocumulene-Mediated Annulation Reaction
β Scribed by Hoesl, Cornelia E.; Nefzi, Adel; Houghten, Richard A.
- Book ID
- 125535255
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 111 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1520-4766
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## Abstract magnified image The carbodiimides **2**, obtained from reactions of iminophosphorane **1** with isocyanates, reacted with hydrazine to give selectively 3βaminoβ2βarylaminobenzothieno[3,2β__d__]pyrimidinβ4(3__H__)βones **4**. Reactions of **4** with triphenylphosphine, hexachloroethane,
## Abstract For Abstract see ChemInform Abstract in Full Text.
An abnormal aza-Wittig reaction was observed when resin-bound iminophosporanes were treated with aryl isocyanates on the solid-phase. The mechanism of the reaction may involve the loss of triphenylphosphinimide instead of triphenylphosphinoxide, resulting in the formation of isocyanates instead of c